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Restylane Defyne


Nasolabial folds are the lines running from the sides of the nose to the mouth corners. They are also known as parentheses lines or smile lines. Marionette are the lines running from the corner of the mouth down the chin. If you are considering facial rejuvenation with dermal fillers, discover Skin Deep, where every procedure is overseen by our physician, Dr. Melody Denham, to ensure high quality results that appear fresh and natural – not overfilled.

As the skin loses elasticity with aging, nasolabial folds and marionette lines start to appear, eventually becoming deeply etched. At Skin Deep MD, we perform non-surgical facial rejuvenation treatments with dermal fillers at our private Boulder clinic. This includes treatment with Restylane Defyne, formulated to correct deepened lines and folds without impacting your facial expression, for natural-looking results that help maintain natural movement.

What Is Restylane Defyne Technology and How Does It Work?

Restylane Defyne is an advanced dermal filler designed to restore a more youthful appearance to the face. It uses innovative XpresHAn Technology™ that provides the flexibility for a natural range of facial expression. This injectable facial filler is made with hyaluronic acid that acts like the HA occurring naturally in the skin.

Cross-linking technology adds flexibility and support to Restylane Defyne. While still highly flexible, it is formulated with more cross-linking than Restylane Refyne, for greater support with less flexibility.


Restylane Defyne, Skindeep What Can I Expect with Restylane Defyne Treatment?

Restylane Defyne treatments can take anywhere from 15 minutes to an hour to perform, depending on the number of areas treated and the number of injections to achieve the perfect look. This hyaluronic acid dermal filler contains lidocaine, a local anesthetic, for more comfortable treatment. For those who have concerns about pain, a topical anesthetic can be applied prior to the injections.

Our aesthetic injector will perform a series of injections beneath your skin with a very fine-gauge needle. These injections are skillfully placed to fill in and smooth deep wrinkles and folds, restoring a more youthful appearance geared to help you maintain your natural expressiveness. You look younger – but like you, not frozen or stiff.

Before we administer dermal fillers in Boulder, you will have consultation with a medical doctor to discuss your medical history, aging concerns, and aesthetic goals. After a careful evaluation of your anatomy, we will tailor a treatment plan specifically for you.


What Are Results Like with Restylane Defyne?

In a clinical study reported by Restylane, researchers evaluated subjects one month after treatment with Restylane Defyne and Restylane Refyne based on naturalness of facial expressions in motion. This was a noncomparative, multicenter trial of 63 subjects ages 35 to 65 years. Researchers found that:

  • 97% (61 out of 63 subjects) were satisfied with their results
  • 97% (61 out of 63 subjects) would have treatment with Restylane Defyne or Refyne again
  • 95% (60 out of 63 subjects) would recommend these products to a friend


Why Have Restylane Defyne Injections?

The signs of facial aging are caused not only by loss of elasticity in the skin, but also by volume loss. When fat volume slowly decreases, and collagen, elastin, and hyaluronic acid break down, it can cause deep folds and creases around the mouth and nose or leave your cheeks looking flat or hollow.

Treatment with Restylane Defyne at Skin Deep MD in Boulder replaces lost hyaluronic acid and facial volume to:

  • Fill in nasolabial folds from the corners of the nose to the mouth corners
  • Smooth marionette lines between the corners of the mouth and the chin and jawline
  • Correct facial wrinkles and folds
  • Rejuvenate the lower face around the mouth
  • Support facial expressions in motion for natural-looking results

Restylane Defyne uses cross-linking technology to help maintain natural movement while creating a more youthful facial look, refreshed and rejuvenated. At our Boulder, CO clinic, Restylane Defyne and all dermal filler injections are skillfully and meticulously performed for better results. Schedule a consultation to find out if Restylane Defyne is the right non-surgical facial rejuvenation treatment for you.


Skin Deep MD
3445 Penrose Pl, Suite 140
Boulder, CO 80301
Phone: 303-586-2964
Fax: 303-413-0300

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